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Publications | Shekh-Ahmad Lab
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Publications

2020
R. Olowe, Sandouka, S. , Saadi, A. , and Shekh‐ahmad, T. . 2020. “Approaches For Reactive Oxygen Species And Oxidative Stress Quantification In Epilepsy”. Antioxidants, 9, 10, Pp. 1-26. doi:10.3390/antiox9100990. Publisher's Version
2019
T. Shekh-Ahmad, Lieb, A. , Kovac, S. , Gola, L. , Wigley, W.C. , Abramov, A.Y. , and Walker, M.C. . 2019. “Combination Antioxidant Therapy Prevents Epileptogenesis And Modifies Chronic Epilepsy”. Redox Biology, 26. doi:10.1016/j.redox.2019.101278. Publisher's Version
A. Snowball, Chabrol, E. , Wykes, R.C. , Shekh-Ahmad, T. , Cornford, J.H. , Lieb, A. , Hughes, M.P. , Massaro, G. , Rahim, A.A. , Hashemi, K.S. , Kullmann, D.M. , Walker, M.C. , and Schorge, S. . 2019. “Epilepsy Gene Therapy Using An Engineered Potassium Channel”. Journal Of Neuroscience, 39, 16, Pp. 3159-3169. doi:10.1523/JNEUROSCI.1143-18.2019. Publisher's Version
A. Pauletti, Terrone, G. , Shekh-Ahmad, T. , Salamone, A. , Ravizza, T. , Rizzi, M. , Pastore, A. , Pascente, R. , Liang, L.-P. , Villa, B.R. , Balosso, S. , Abramov, A.Y. , van Vliet, E.A. , Giudice, E.D. , Aronica, E. , Patel, M. , Walker, M.C. , and Vezzani, A. . 2019. “Notice Of Retraction: Targeting Oxidative Stress Improves Disease Outcomes In A Rat Model Of Acquired Epilepsy (Brain (2017) 140, (1885–1899) Doi:10.1093/Brain/Awx117)”. Brain, 142, 7. doi:10.1093/brain/awz128. Publisher's Version
T. Shekh-Ahmad, Kovac, S. , Abramov, A.Y. , and Walker, M.C. . 2019. “Reactive Oxygen Species In Status Epilepticus”. Epilepsy And Behavior, 101. doi:10.1016/j.yebeh.2019.07.011. Publisher's Version
A. Pauletti, Terrone, G. , Shekh-Ahmad, T. , Salamone, A. , Ravizza, T. , Rizzi, M. , Pastore, A. , Pascente, R. , Liang, L.-P. , Villa, B.R. , Balosso, S. , Abramov, A.Y. , van Vliet, E.A. , Giudice, E.D. , Aronica, E. , Patel, M. , Walker, M.C. , and Vezzani, A. . 2019. “Targeting Oxidative Stress Improves Disease Outcomes In A Rat Model Of Acquired Epilepsy”. Brain, 142, 7. doi:10.1093/brain/awz130. Publisher's Version
2018
A.A. Khan, Shekh-Ahmad, T. , Khalil, A. , Walker, M.C. , and Ali, A.B. . 2018. “Cannabidiol Exerts Antiepileptic Effects By Restoring Hippocampal Interneuron Functions In A Temporal Lobe Epilepsy Model”. British Journal Of Pharmacology, 175, 11, Pp. 2097-2115. doi:10.1111/bph.14202. Publisher's Version
T. Shekh-Ahmad, Eckel, R. , Dayalan Naidu, S. , Higgins, M. , Yamamoto, M. , DInkova-Kostova, A.T. , Kovac, S. , Abramov, A.Y. , and Walker, M.C. . 2018. “Keap1 Inhibition Is Neuroprotective And Suppresses The Development Of Epilepsy”. Brain, 141, 5, Pp. 1390-1403. doi:10.1093/brain/awy071. Publisher's Version
2017
M. Weiser, Levi, L. , Levine, S.Z. , Bialer, M. , Shekh-Ahmad, T. , Matei, V. , Tiugan, A. , Cirjaliu, D. , Sava, C. , Sinita, E. , Zamora, D. , and Davis, J.M. . 2017. “A Randomized, Double-Blind, Placebo- And Risperidone-Controlled Study On Valnoctamide For Acute Mania”. Bipolar Disorders, 19, 4, Pp. 285-294. doi:10.1111/bdi.12506. Publisher's Version
A. Pauletti, Terrone, G. , Shekh-Ahmad, T. , Salamone, A. , Ravizza, T. , Rizzi, M. , Pastore, A. , Pascente, R. , Liang, L.-P. , Villa, B.R. , Balosso, S. , Abramov, A.Y. , van Vliet, E.A. , Del Giudice, E. , Aronica, E. , Antoine, D.J. , Patel, M. , Walker, M.C. , and Vezzani, A. . 2017. “Targeting Oxidative Stress Improves Disease Outcomes In A Rat Model Of Acquired Epilepsy”. Brain, 140, 7, Pp. 1885-1899. doi:10.1093/brain/awx117. Publisher's Version
2016
H. Mawasi, Bibi, D. , Shekh-Ahmad, T. , Shaul, C. , Blotnik, S. , and Bialer, M. . 2016. “Pharmacokinetic-Pharmacodynamic Correlation And Brain Penetration Of Sec-Butylpropylacetamide, A New Cns Drug Possessing Unique Activity Against Status Epilepticus”. Molecular Pharmaceutics, 13, 7, Pp. 2492-2496. doi:10.1021/acs.molpharmaceut.6b00221. Publisher's Version
2015
H. Mawasi, Shekh-Ahmad, T. , Finnell, R.H. , Wlodarczyk, B.J. , and Bialer, M. . 2015. “Pharmacodynamic And Pharmacokinetic Analysis Of Cns-Active Constitutional Isomers Of Valnoctamide And Sec-Butylpropylacetamide - Amide Derivatives Of Valproic Acid”. Epilepsy And Behavior, 46, Pp. 72-78. doi:10.1016/j.yebeh.2015.02.040. Publisher's Version
T. Shekh-Ahmad, Mawasi, H. , McDonough, J.H. , Yagen, B. , and Bialer, M. . 2015. “The Potential Of Sec-Butylpropylacetamide (Spd) And Valnoctamide And Their Individual Stereoisomers In Status Epilepticus”. Epilepsy And Behavior, 49, Pp. 298-302. doi:10.1016/j.yebeh.2015.04.012. Publisher's Version
2014
T. Shekh-Ahmad, Mawasi, H. , McDonough, J.H. , Finnell, R.H. , Wlodarczyk, B.J. , Yavin, E. , and Bialer, M. . 2014. “Enantioselective Pharmacodynamic And Pharmacokinetic Analysis Of Two Chiral Cns-Active Carbamate Derivatives Of Valproic Acid”. Epilepsia, 55, 12, Pp. 1944-1952. doi:10.1111/epi.12857. Publisher's Version
G. Bar-Klein, Swissa, E. , Kamintsky, L. , Shekh-Ahmad, T. , Saar-Ashkenazy, R. , Hubary, Y. , Shrot, S. , Stetlander, L. , Eisenkraft, A. , Friedman, A. , and Bialer, M. . 2014. “Sec-Butyl-Propylacetamide (Spd) And Two Of Its Stereoisomers Rapidly Terminate Paraoxon-Induced Status Epilepticus In Rats”. Epilepsia, 55, 12, Pp. 1953-1958. doi:10.1111/epi.12838. Publisher's Version
T. Shekh-Ahmad, Hen, N. , Yagen, B. , McDonough, J.H. , Finnell, R.H. , Wlodarczyk, B.J. , and Bialer, M. . 2014. “Stereoselective Anticonvulsant And Pharmacokinetic Analysis Of Valnoctamide, A Cns-Active Derivative Of Valproic Acid With Low Teratogenic Potential”. Epilepsia, 55, 2, Pp. 353-361. doi:10.1111/epi.12480. Publisher's Version
2013
W. Pouliot, Bialer, M. , Hen, N. , Shekh-Ahmad, T. , Kaufmann, D. , Yagen, B. , Ricks, K. , Roach, B. , Nelson, C. , and Dudek, F.E. . 2013. “A Comparative Electrographic Analysis Of The Effect Of Sec-Butyl-Propylacetamide On Pharmacoresistant Status Epilepticus”. Neuroscience, 231, Pp. 145-156. doi:10.1016/j.neuroscience.2012.11.005. Publisher's Version
M. Bialer, Shekh-Ahmad, T. , Braun, T.L. , and Halvorsen, M.B. . 2013. “Comparative Steady-State Pharmacokinetic Evaluation Of Immediate-Release Topiramate And Usl255, A Once-Daily Extended-Release Topiramate Formulation”. Epilepsia, 54, 8, Pp. 1444-1452. doi:10.1111/epi.12225. Publisher's Version
N. Hen, Shekh-Ahmad, T. , Yagen, B. , McDonough, J.H. , Finnell, R.H. , Wlodarczyk, B. , and Bialer, M. . 2013. “Stereoselective Pharmacodynamic And Pharmacokinetic Analysis Of Sec -Butylpropylacetamide (Spd), A New Cns-Active Derivative Of Valproic Acid With Unique Activity Against Status Epilepticus”. Journal Of Medicinal Chemistry, 56, 16, Pp. 6467-6477. doi:10.1021/jm4007565. Publisher's Version
T. Shekh-Ahmad, Hen, N. , McDonough, J.H. , Yagen, B. , and Bialer, M. . 2013. “Valnoctamide And Sec-Butyl-Propylacetamide (Spd) For Acute Seizures And Status Epilepticus”. Epilepsia, 54, SUPPL. 6, Pp. 99-102. doi:10.1111/epi.12290. Publisher's Version